Grignard Reagents vs Gilman Reagents | 20.4 Organic Chemistry

Chad gives a succinct lesson on the reactions of Grignard Reagents and Gilman Reagents (organometallics) with carboxylic acid derivatives. The reaction of acid halides, acid anhydrides, and esters with excess Grignard reagents are explained with the reaction of a Grignard reagent with an ester being the most commonly tested upon. The lesson is concluded with the Gilman reaction which involves the reaction of acid halides and acid anhydrides with one equivalent of the less reactive Gilman reagent (an organocuprate).

I’ve created an organic chemistry page that organizes all my videos by chapter – just an easier way for you to watch my YouTube videos. Check it out at https://www.chadsprep.com/organic-chemistry-youtube

00:00 Lesson Introduction
00:31 Reactions with Grignard Reagents
03:33 Reactions with Gilman Reagents

https://www.chadsprep.com/
#grignardreagent #organometallics #organicchemistry