Acidity of Terminal Alkynes | 9.2 Organic Chemistry

Alkyne Acidity
Chad reveals that terminal alkynes (pKa ~ 26) are considerably more acidic than a typical alkene (pKa ~ 44) or alkane (pKa ~ 50). He then goes on to show that sodium amide, NaNH2, is typically the preferred base for deprotonating a terminal alkyne to form an acetylide ion as sodium hydroxide, NaOH, is not strong enough to carry out this reaction.

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00:00 Introduction
00:38 The Acidity of a Terminal Alkyne (pKa ~ 26)
02:42 Deprotonating a Terminal Alkyne with NaNH2

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