Phenylketonuria & Cystic Fibrosis | Inborn Errors of Metabolism NEET Class 12 | Neela Bakore

◀ PREVIOUS VIDEO (21/36): Haemophilia

▶ CURRENT VIDEO (22/36): Phenylketonuria & Cystic Fibrosis

▶ NEXT VIDEO (23/36): Thalassaemia & Colour Blindness

🔗 Full Playlist: https://www.youtube.com/playlist?list=PLr5BFsBzRyFTujMChFMNDOZdHGS8u-Fng
━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
Phenylketonuria (PKU) and Cystic Fibrosis — two key autosomal recessive disorders in detail.

📌 Topics Covered:
• PKU: phenylalanine hydroxylase deficiency → brain damage; neonatal screening
• Cystic Fibrosis: CFTR mutation → thick mucus in lungs, pancreas, gut
• Both autosomal recessive; comparison table
• NEET MCQ patterns for metabolic disorders
━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
Transcript with Timestamp
0:00 Introduction — PKU and Cystic Fibrosis
0:17 PKU (Phenylketonuria) — autosomal recessive disorder
0:43 Enzyme absent: Phenylalanine hydroxylase
1:19 Pathway: Phenylalanine → Tyrosine (blocked in PKU)
1:39 Phenylalanine accumulates → converted to Phenylpyruvic acid → brain damage
2:37 Babies born with PKU — metabolic disorder
2:50 Cystic Fibrosis (CF) — autosomal recessive disorder
3:37 Caused by deletion of nitrogen base
3:49 Accumulation of glycoproteins → thick mucus in liver, pancreas, respiratory tract
4:41 Transmembrane conduction protein affected → chloride ion transport impaired
5:37 Sweat becomes saltier (↑ NaCl)
━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
Amazon Brand Store at https://www.amazon.in/neelabakoretutorials.
Complete Study Notes (11th and 12th) are available at: https://amzn.to/3K4Li7k
Complete Study Notes for 12th are available at: https://amzn.to/3PRhWjm
Complete Study Notes for 11th are available at: https://amzn.to/4uw1hBa
The study notes for this unit Genetics & Evolution are available at https://amzn.to/2Sh27jW

The study notes for other units: –
Diversity in Living World – https://amzn.to/3r8qkyH
Structural Organisation in Plants and Animals – https://amzn.to/3r2cxmZ
Cell: Structure and Functions – https://amzn.to/2GPagcm
Plant Physiology – http://amzn.to/2EZR5HS
Human Physiology – http://amzn.to/2DA46ea
Reproduction – https://amzn.to/2wu43eS
Biotechnology – http://amzn.to/2EZyqf9
Biology in Human Welfare https://amzn.to/4dPRZd7
Ecology https://amzn.to/3RwuOvF
____________________________________________
For business inquiries: abhibakore@gmail.com
___________________________________________

#Phenylketonuria #CysticFibrosis #InbornErrorsOfMetabolism #NEETBiology #GeneticsClass12 #NeelaBakoreTutorials