Metabolism | Amino Acid Metabolism

📚 Premium Notes & Illustrations for Amino Acid Metabolism: https://www.ninjanerd.org/lecture/amino-acid-metabolism-2

Ninja Nerds!
In this metabolism lecture, Professor Zach Murphy discusses Amino Acid Metabolism, focusing on how the body utilizes, transforms, and disposes of amino acids in both fed and fasting states. This lecture helps you connect protein catabolism to energy production, glucose synthesis, and nitrogen balance across multiple organ systems.

We review how amino acids are obtained through dietary protein digestion and used for protein synthesis, energy production, or biosynthetic pathways. The lecture then covers transamination and deamination reactions—processes that remove or transfer amino groups—highlighting enzymes like aminotransferases and glutamate dehydrogenase.

You’ll learn how nitrogen is safely removed through the urea cycle, and how carbon skeletons are classified as glucogenic, ketogenic, or both. Depending on the metabolic state, we explore how these skeletons feed into gluconeogenesis, the TCA cycle, or ketone body formation.

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